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1

Personalized medicine: a patient - centered paradigm

Lotfi Chouchane, Ravinder Mamtani, Ashraf Dallol, Javaid I Sheikh

Journal:

Journal of Translational Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 108 KB

english, 2011

2

RASSF2 associates with and stabilizes the proapoptotic kinase MST2

Cooper, W N, Hesson, L B, Matallanas, D, Dallol, A, von Kriegsheim, A, Ward, R, Kolch, W, Latif, F

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 495 KB

english, 2009

3

The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

Yu, J, Cao, Q, Yu, J, Wu, L, Dallol, A, Li, J, Chen, G, Grasso, C, Cao, X, Lonigro, R J

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 829 KB

english, 2010

4

SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma

Astuti, D, da Silva, N F, Dallol, A, Gentle, D, Martinsson, T, Kogner, P, Grundy, R, Kishida, T, Yao, M, Latif, F

Journal:

British Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 147 KB

english, 2004

5

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours

Agathanggelou, Angelo, Honorio, Sofia, Macartney, Donia P, Martinez, Alonso, Dallol, Ashraf, Rader, Janet, Fullwood, Paul, Chauhan, Anita, Walker, Rosemary, Shaw, Jacqueline A

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 422 KB

english, 2001

6

RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours

Astuti, Dewi, Agathanggelou, Angelo, Honorio, Sofia, Dallol, Ashraf, Martinsson, Tommy, Kogner, Per, Cummins, Carole, Neumann, Hartmut PH, Voutilainen, Raimo, Dahia, Patricia

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 178 KB

english, 2001

7

Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

Dallol, Ashraf, Forgacs, Eva, Martinez, Alonso, Sekido, Yoshitaka, Walker, Rosemary, Kishida, Takeshi, Rabbitts, Pamela, Maher, Eamonn R, Minna, John D, Latif, Farida

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 399 KB

english, 2002

8

Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers

Agathanggelou, Angelo, Dallol, Ashraf, Zöchbauer-Müller, Sabine, Morrissey, Catherine, Honorio, Sofia, Hesson, Luke, Martinsson, Tommy, Fong, Kwun M, Kuo, Michael J, Yuen, Po Wing

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 493 KB

english, 2003

9

NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers

Hesson, Luke, Dallol, Ashraf, Minna, John D, Maher, Eamonn R, Latif, Farida

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 327 KB

english, 2003

10

Frequent epigenetic inactivation of the SLIT2 gene in gliomas

Dallol, Ashraf, Krex, Dietmar, Hesson, Luke, Eng, Charis, Maher, Eamonn R, Latif, Farida

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 285 KB

english, 2003

11

Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer

Cooper, W N, Dickinson, R E, Dallol, A, Grigorieva, E V, Pavlova, T V, Hesson, L B, Bieche, I, Broggini, M, Maher, E R, Zabarovsky, E R

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 320 KB

english, 2007

12

RAN GTPase Is a RASSF1A Effector Involved in Controlling Microtubule Organization

Ashraf Dallol, Luke B. Hesson, David Matallanas, Wendy N. Cooper, Eric O'Neill, Eamonn R. Maher, Walter Kolch, Farida Latif

Journal:

Current Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2009

13

Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma

R.P Hogg, S Honorio, A Martinez, A Agathanggelou, A Dallol, P Fullwood, R Weichselbaum, M.J Kuo, E.R Maher, F Latif

Journal:

European Journal of Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 349 KB

english, 2002

14

Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma

Dewi Astuti, Farida Latif, Ashraf Dallol, Patricia L.M. Dahia, Fiona Douglas, Emad George, Filip Sköldberg, Eystein S. Husebye, Charis Eng, Eamonn R. Maher

Journal:

The American Journal of Human Genetics

Année:

2001

Langue:

english

Fichier:

PDF, 685 KB

english, 2001

15

Methylation of the Polycomb Group Target Genes Is a Possible Biomarker for Favorable Prognosis in Colorectal Cancer

Dallol, A., Al-Maghrabi, J., Buhmeida, A., Gari, M. A., Chaudhary, A. G., Schulten, H.-J., Abuzenadah, A. M., Al-Ahwal, M. S., Sibiany, A., Al-Qahtani, M. H.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Année:

2012

Langue:

english

Fichier:

PDF, 603 KB

english, 2012

16

P-299 Epigenetic inactivation of the candidate tumor suppressor gene SLIT-2 in SCLC and NSCLC lung cancers

Morrissey, Catherine, Toyooka, Shinichi, Fong, Kwun, Dallol, Ashraf, Latif, Farida, Gazdar, Adi, Minna, John D.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 188 KB

english, 2003

17

A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

Thomas Dunwell, Luke Hesson, Tibor A Rauch, Lihui Wang, Richard E Clark, Ashraf Dallol, Dean Gentle, Daniel Catchpoole, Eamonn R Maher, Gerd P Pfeifer, Farida Latif

Journal:

Molecular Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2010

18

Identification of 5 novel genes methylated in breast and other epithelial cancers

Victoria K Hill, Luke B Hesson, Temuujin Dansranjavin, Ashraf Dallol, Ivan Bieche, Sophie Vacher, Stella Tommasi, Timothy Dobbins, Dean Gentle, David Euhus, Cheryl Lewis, Reinhard Dammann, Robyn L War

Journal:

Molecular Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2010

19

Five novel glucose-6-phosphate dehydrogenase deficiency haplotypes correlating with disease severity

Ashraf Dallol, Huda Banni, Mamdooh A Gari, Mohammed H Al-Qahtani, Adel M Abuzenadeh, Fatin Al-Sayes, Adeel G Chaudhary, Jeffrey Bidwell, Wael Kafienah

Journal:

Journal of Translational Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 232 KB

english, 2012

20

RASSF2 can suppress the growth of breast cancer cell lines and is epigenetically inactivated in breast tumours

WN Cooper, RE Dickinson, A Dallol, LB Hesson, I Bieche, GJ Clark…

Journal:

Breast Cancer Research

Année:

2008

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2008

21

Spectrum of GJB2 Mutations in a Cohort of Nonsyndromic Hearing Loss Cases from the Kingdom of Saudi Arabia

Al-Qahtani, Mohammed H., Baghlab, Ibtessam, Chaudhary, Adeel G., Abuzenadah, Adel M., Bamanie, Afaf, Daghistani, Kamal J., Safieh, Malek, Fida, Loai, Dallol, Ashraf

Journal:

Genetic Testing and Molecular Biomarkers

Année:

2010

Langue:

english

Fichier:

PDF, 234 KB

english, 2010

22

High fibroblast growth factor 19 (FGF19) expression predicts worse prognosis in invasive ductal carcinoma of breast

Buhmeida, Abdelbaset, Dallol, Ashraf, Merdad, Adnan, Al-Maghrabi, Jaudah, Gari, Mamdooh A., Abu-Elmagd, Muhammad M., Chaudhary, Adeel G., Abuzenadah, Adel M., Nedjadi, Taoufik, Ermiah, Eramah, Al-Thub

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 432 KB

english, 2014

23

Cell adhesion molecules have prognostic potential in colorectal carcinoma

AL-Attas, Asma’a, AlMalki, Abdulrhaman, Gari, Mamdooh, Mathew, Shilu, Al-Maghrabi, Jaudah, Al-Ahwal, Mahmoud, Al-Qahtani, Mohammed, Dallol, Ashraf, Buhmeida, Abdelbaset

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 74 KB

english, 2014

24

Prognostic significance of fibroblast growth factor 19 (FGF19) expression in breast invasive ductal carcinoma

Hakamy, Sahar, Abdallah, Basmat, Buhmeida, Abdelbaset, Dallol, Ashraf, Merdad, Adnan, Al-Maghrabi, Jaudah, Abu-Elmagd, Muhammad, Gari, Mamdooh, Chaudhary, Adeel, Abuzenadah, Adel, Nedjadi, Taoufik, Er

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 86 KB

english, 2014

25

Mismatch repair genes status in sporadic Saudi colorectal cancer patients

Ata, Manar, Dallol, Ashraf, Al-Maghrabi, Jaudah, Al-Sibiany, Abdulrahmn, Al-Ahwal, Mahmoud, Al-Qahtani, Mohammed, Buhmeida, Abdelbaset

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 73 KB

english, 2014

26

Investigation of the genetic causes of non-syndromic hearing loss in the Western region of Saudi Arabia

Daghistani, Kamal, Abdulkarim, Angham, Bamanie, Afaf, Safieh, Malek, Sogaty, Samira, Al-Shaikh, Abdulmonem, Abulnaja, Khalid O, Ata, Manar, Dallol, Ashraf

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 67 KB

english, 2014

27

Molecular characterization and identification of predictors of disease outcome in Saudi colorectal carcinoma

Buhmeida, Abdelbaset, Dallol, Ashraf, Al-Maghrabi, Jaudah, Al-Ahwal, Mahmoud, Sibiany, Abdulrahman, Al-Qahtani, Mohmmad

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 74 KB

english, 2014

28

Identification of frequent MTNR1B methylation in breast cancer following the application of high-throughput methylome analysis

Mathew, Shylu, Merdad, Adnan, Al-Maghrabi, Jaudah, Dallol, Ashraf

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 73 KB

english, 2014

29

Gene expression profiling of lymph node positive-negative metastasis of primary breast cancer in Saudi Arabian patients

Merdad, Adnan, Karim, Sajjad, Schulten, Hans-Juergen, Dallol, Ashraf, Buhmeida, Abdelbaset S, Al-Thubaity, Fatima, Ata, Manar M, Gari, Mamdooh A, Chaudhary, Adeel GA, Abuzenadah, Adel M, Al-Qahtani, M

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 86 KB

english, 2014

30

The role of MTNR1B genetic polymorphisms in type 2 diabetes mellitus

Shaer, Nehad, Khan, Jalaluddin J, Dallol, Ashraf, Abuzenadah, Adel

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 75 KB

english, 2014

31

Array Comparative Genomic hybridization of breast cancer in the kingdom of Saudi Arabia

Al-Harbi, Lina, Shokry, Ahmed, Sabir, Jamal, Chaudhary, Adeel, Dallol, Ashraf

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 80 KB

english, 2014

32

Diabetes personalized: the use of whole-exome sequencing in order to identify familial type 2 diabetes mellitus susceptibility factors

Shaer, Nehad, Khan, Jalaluddin J, Dallol, Ashraf, Abuzenadah, Adel

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 74 KB

english, 2014

33

Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers

Dickinson, R E, Dallol, A, Bieche, I, Krex, D, Morton, D, Maher, E R, Latif, F

Journal:

British Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 149 KB

english, 2004

34

RASSF2 methylation is a strong prognostic marker in younger age patients with Ewing sarcoma

Gharanei, Seley, Brini, Anna T, Vaiyapuri, Sumathi, Alholle, Abdullah, Dallol, Ashraf, Arrigoni, Elena, Kishida, Takeshi, Hiruma, Toru, Avigad, Smadar, Grimer, Robert, Maher, Eamonn R, Latif, Farida

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2013

35

The RASSF1A Tumor Suppressor Activates Bax via MOAP-1

Vos, M. D., Dallol, A., Eckfeld, K., Allen, N. P. C., Donninger, H., Hesson, L. B., Calvisi, D., Latif, F., Clark, G. J.

Journal:

Journal of Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 825 KB

english, 2006

36

Depletion of the Ras Association Domain Family 1, Isoform A-Associated Novel Microtubule-Associated Protein, C19ORF5/MAP1S, Causes Mitotic Abnormalities

Dallol, A., Cooper, W. N., Al-Mulla, F., Agathanggelou, A., Maher, E. R., Latif, F.

Journal:

Cancer Research

Année:

2007

Langue:

english

Fichier:

PDF, 664 KB

english, 2007

37

Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability

Al-Mulla, F, Hagan, S, Al-Ali, W, Jacob, S P, Behbehani, A I, Bitar, M S, Dallol, A, Kolch, W

Journal:

Journal of Clinical Pathology

Année:

2008

Langue:

english

Fichier:

PDF, 490 KB

english, 2008

38

Exome Sequencing of Normal and Isogenic Transformed Human Colonic Epithelial Cells (HCECs) Reveals Novel Genes Potentially Involved in the Early Stages of Colorectal Tumorigenesis

Zhang, Lu, Kim, Sang, Jia, Gaoxiang, Buhmeida, Abdelbaset, Dallol, Ashraf, Wright, Woodring E, Fornace, Albert J, Al-Qahtani, Mohammed, Shay, Jerry W

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2015

39

Individualized medicine enabled by genomics in Saudi Arabia

Abu-Elmagd, Muhammad, Assidi, Mourad, Schulten, Hans-Juergen, Dallol, Ashraf, Pushparaj, Peter, Ahmed, Farid, Scherer, Stephen W, Al-Qahtani, Mohammed

Journal:

BMC Medical Genomics

Année:

2015

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2015

40

RASSF1A Interacts with Microtubule-Associated Proteins and Modulates Microtubule Dynamics

Journal:

Cancer Research

Année:

2004

Langue:

english

Fichier:

PDF, 433 KB

english, 2004

41

Frequent methylation of the KLOTHO gene and overexpression of the FGFR4 receptor in invasive ductal carcinoma of the breast

Dallol, Ashraf, Buhmeida, Abdelbaset, Merdad, Adnan, Al-Maghrabi, Jaudah, Gari, Mamdooh A., Abu-Elmagd, Muhammad M., Elaimi, Aisha, Assidi, Mourad, Chaudhary, Adeel G., Abuzenadah, Adel M., Nedjadi, T

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

42

Functional epigenetic approach identifies frequently methylated genes in Ewing sarcoma

Alholle, Abdullah, Brini, Anna T, Gharanei, Seley, Vaiyapuri, Sumathi, Arrigoni, Elena, Dallol, Ashraf, Gentle, Dean, Kishida, Takeshi, Hiruma, Toru, Avigad, Smadar, Grimer, Robert, Maher, Eamonn R, L

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2013

43

Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia

Dunwell, Thomas L., Dickinson, Rachel E., Stankovic, Tatjana, Dallol, Ashraf, Weston, Victoria, Austen, Belinda, Catchpoole, Daniel, Maher, Eamonn R., Latif, Farida

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2009

44

Detection of β-Thalassemia Mutations Using TaqMan Single Nucleotide Polymorphism Genotyping Assays

Alwazani, Wissam A., Zahid, Rawabi, Elaimi, Aisha, Bajouh, Osamah, Hindawi, Salwa, Arab, Badr, Damanhouri, Ghazi, Saka, Mohamad Yassin, Turki, Rola, Khan, Jalaluddin A., Dallol, Ashraf, Abuzenadah, Ad

Journal:

Genetic Testing and Molecular Biomarkers

Année:

2016

Langue:

english

Fichier:

PDF, 262 KB

english, 2016

45

When RASSF1A RAN into tumor suppression: Ran GTPase is a RASSF1A effector involved in controlling microtubule organization

Dallol, Ashraf, Kolch, Walter, Latif, Farida

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 810 KB

english, 2009

46

Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples

Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Ahwal, Mahmoud Shaheen, Al-Maghrabi, Jaudah, Bajouh, Osama, Al-Khayyat, Shadi, Alam, Rania, Abusanad, Atlal, Turki, Rola, Elaimi, Aisha, Alhadrami, Hani A., Ab

Journal:

Journal of Translational Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2016

47

Transcriptomics profiling study of breast cancer from Kingdom of Saudi Arabia revealed altered expression ofAdiponectinandFatty Acid Binding Protein4: Is lipid metabolism associated with breast cancer?

Merdad, Adnan, Karim, Sajjad, Schulten, Hans-Juergen, Jayapal, Manikandan, Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Thubaity, Fatima, GariI, Mamdooh A, Chaudhary, Adeel GA, Abuzenadah, Adel M, Al-Qaht

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.33 MB

english, 2015

48

62 * VIRTUAL WARD EXPERIENCE

Dallol, B., Pinkney, M.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 39 KB

english, 2014

49

Low expression of leptin and its association with breast cancer: A transcriptomic study

Karim, Sajjad, Merdad, Adnan, Schulten, Hans-Juergen, Jayapal, Manikandan, Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Thubaity, Fatima, Mirza, Zeenat, Gari, Mamdooh, Chaudhary, Adeel, Abuzenadah, Adel,

Journal:

Oncology Reports

Année:

2016

Langue:

english

Fichier:

PDF, 752 KB

english, 2016

50

Prognostic value of HER2 status in bladder transitional cell carcinoma revealed by both IHC and BDISH techniques

Nedjadi, Taoufik, Al-Maghrabi, Jaudah, Assidi, Mourad, Dallol, Ashraf, Al-Kattabi, Heba, Chaudhary, Adeel, Al-Sayyad, Ahmed, Al-Ammari, Adel, Abuzenadah, Adel, Buhmeida, Abdelbaset, Al-Qahtani, Mohamm

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2016